Resumen

Cancer is a disease that affects humans all over the world. Nanotechnology is a tool that has been exploited in recent years for the treatment of cancer. Compared to conventional anticancer treatments, nanotechnology provides specificity and precise targeting. When irradiated with infrared radiation, magnetic nanoparticles are heated and cause hyperthermia, specifically affecting cancerous cells. A specific type of nanomaterial called magnetic core/shell nanoparticle can have improved properties that may be used in magnetic hyperthermia. Furthermore, these nanoparticles can be functionalized with organic molecules, like L-glutamic acid, to enhance their properties. The literature review, as well as the synthesis and characterization of L-glutamic acid functionalized core/shell nanoparticles using magnetite and gold as the core and shell materials interchangeably, prove that these nanoparticles could be used as potential treatment against cancer based on magnetic hyperthermia.

Keywords: Metallic nanoparticles, nanomedicine, anticancer materials, cancer, L-glutamic acid, magnetite nanoparticles, gold nanoparticles, core/shell nanoparticles.

Esta tesis sólo puede ser consultada por miembros de la Comunidad Universitaria. (ir al índice de contenido)

Rivera Fuentes, D. E. 2023. Synthesis of Core/shell Nanoparticles Functionalized with Glutamic Acid as a Potential Use Against Cancer. Tesis Licenciatura. Nanotecnología e Ingeniería Molecular. Departamento de Ciencias Químico Biológicas, Escuela de Ciencias, Universidad de las Américas Puebla. Diciembre. Derechos Reservados © 2023.